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Mitochondrial Aspects Of Neuronal Pathology In Triple-Transgenic Alzheimer’S Disease Mice, John Zachary Cavendish 2021 West Virginia University

Mitochondrial Aspects Of Neuronal Pathology In Triple-Transgenic Alzheimer’S Disease Mice, John Zachary Cavendish

Graduate Theses, Dissertations, and Problem Reports

Alzheimer’s disease (AD) is a fatal, progressive neurodegenerative disease afflicting millions of people in the United States alone and is the only one of the top leading causes of morbidity and mortality with no effective disease-modifying therapies. It is the most common form of dementia, affecting one in three people over the age of 85. While the hallmarks of the disease include accumulation of beta-amyloid-based extracellular plaques and hyperphosphorylated tau-based intracellular neurofibrillary tangles, treatment strategies centered on removing or mitigating these components of AD have all failed in humans. Mitochondrial dysfunction has been increasingly recognized as an early and ...


Promoting Measles Prevention And Awareness, Elizabeth P. Lanata 2021 University of Vermont

Promoting Measles Prevention And Awareness, Elizabeth P. Lanata

Family Medicine Clerkship Student Projects

No abstract provided.


Charge Nurse Orientation, Angela Zafke 2020 UND

Charge Nurse Orientation, Angela Zafke

Nursing Capstones

Traditional undergraduate training focuses heavily on clinical skills with minimal emphasis on leadership. In practice, a nurse with clinical prowess is often promoted to the charge nurse position. Taking on the leadership role of a charge nurse can be a stressful experience without proper training and preparation that leads to burnout and turnover. With more experienced nurses facing retirement, now is the time to prepare future nursing leaders. This starts with adequately preparing a nurse to lead within the unit in the charge nurse role. A comprehensive literature review was conducted regarding charge nurse orientation. Charge nurse competencies were not ...


Oral Chemotherapy: Safe Handling In The Home, Cynthia Huff 2020 The University of San Francisco

Oral Chemotherapy: Safe Handling In The Home, Cynthia Huff

DNP Qualifying Manuscripts

Background: According to the National Institute for Occupational Safety and Health (2016), oral anticancer agents (OAC) are hazardous drugs (HD) and require the same safe handling interventions in the home setting as in controlled health care environments. The use of a safe handling checklist for OAC administration is a way nurses can provide safe handling education to patients and caregivers and assess for understanding and competency for critical tasks. Effective home management strategies outlining caregiver protections, proper storage, administration of OACs, spill clean-up, and waste disposal could reduce exposure risks to toxic agents.

Objective: To present a safe-handling checklist and ...


Usp Compliance: A Hazardous Drug Safe Handling Ppe Toolkit For Infusion Nurses, Cynthia Huff 2020 The University of San Francisco

Usp Compliance: A Hazardous Drug Safe Handling Ppe Toolkit For Infusion Nurses, Cynthia Huff

Doctor of Nursing Practice (DNP) Projects

Problem: Safety concerns have existed for more than 40 years about how hazardous drug (HD) exposure contributes to long- and short-term adverse health outcomes for healthcare workers (HCWs). Careless handling may cause toxic residues to infiltrate hospital environments and patient care areas, and can even be traced to patients’ homes. New government regulations will require healthcare organizations to minimize exposure risks to HCWs by fully implementing the U.S. Pharmacopeia (USP) Convention Chapter 800: Hazardous Drugs: Handling in Healthcare Settings (USP, 2016) on December 1, 2019. According to Polovich and Olsen (2017), “The implementation of the USP <800> Standards will represent ...


Improving Nurse Engagement Through Unit Practice Councils: A Literature Review, Pavna Sloan 2020 The University of San Francisco

Improving Nurse Engagement Through Unit Practice Councils: A Literature Review, Pavna Sloan

Doctor of Nursing Practice (DNP) Projects

Problem: According to The Advisory Board Company, nurses are the least engaged group of healthcare employees (The Advisory Board Company, 2014). This finding concerns healthcare organizations because those with a high percentage of disengaged nurses have increased nurse turnover rates and decreased patient satisfaction and safety scores (Kutney-Lee et al., 2016). Shared governance, in the form of the Unit Practice Councils (UPC), is a model healthcare organizations implement to increase nurse engagement. A review of the current literature is needed to evaluate if the model is effective.

Purpose: The purpose of this article is to provide a comprehensive literature review ...


Predictors Of Opioid And Alcohol Pharmacotherapy Initiation At Hospital Discharge Among Patients Seen By An Inpatient Addiction Consult Service, Honora Englander, Caroline King, Christina Nicolaidis, Devin Collins, Alisa Patten, Jessica Gregg, P. Todd Korthuis 2020 Oregon Health & Science University

Predictors Of Opioid And Alcohol Pharmacotherapy Initiation At Hospital Discharge Among Patients Seen By An Inpatient Addiction Consult Service, Honora Englander, Caroline King, Christina Nicolaidis, Devin Collins, Alisa Patten, Jessica Gregg, P. Todd Korthuis

Social Work Faculty Publications and Presentations

Background:

Medications for opioid use disorder (MOUD) and alcohol use disorder (MAUD) are effective and under-prescribed. Hospital-based addiction consult services can engage out-of-treatment adults in addictions care. Understanding which patients are most likely to initiate MOUD and MAUD can inform interventions and deepen understanding of hospitals’ role in addressing substance use disorders (SUD).

Objective:

Determine patient- and consult-service level characteristics associated with MOUD/MAUD initiation during hospitalization.

Methods:

We analyzed data from a study of the Improving Addiction Care Team (IMPACT), an interprofessional hospital-based addiction consult service at an academic medical center. Researchers collected patient surveys and clinical data from ...


The Effects Of Increasing Running Speed On Vgrf And Asymmetry, Kaela M. Hierholzer 2020 East Tennessee State University

The Effects Of Increasing Running Speed On Vgrf And Asymmetry, Kaela M. Hierholzer

Electronic Theses and Dissertations

Biomechanical and physiological parameters related to running performance are usually studied separately. However, evaluating both aspects together could be beneficial in improving athletic performance. The purpose of this study was to observe the change in peak vGRF and asymmetry as speed increases, while observing physiological responses during a O2maxtest. Data from athlete monitoring of 12 cross-country and triathlon athletes were analyzed. The athlete monitoring protocol included three unweighted countermovement jumps and a O2maxtest performed by the athletes. The athletes had an average O2maxof 53.4 ± 7.7 mL/kg/min, while their average vGRF ...


"A Comparison Of Variable Selection Methods Using Bootstrap Samples From Environmental Metal Mixture Data", Paul-Yvann Djamen 4785403, Paul-Yvann Djamen 2020 University Of New Mexico

"A Comparison Of Variable Selection Methods Using Bootstrap Samples From Environmental Metal Mixture Data", Paul-Yvann Djamen 4785403, Paul-Yvann Djamen

Mathematics & Statistics ETDs

In this thesis, I studied a newly developed variable selection method SODA, and three customarily used variable selection methods: LASSO, Elastic net, and Random forest for environmental mixture data. The motivating datasets have neuro-developmental status as responses and metal measurements and demographic variables as covariates. The challenges for variable selections include (1) many measured metal concentrations are highly correlated, (2) there are many possible ways of modeling interactions among the metals, (3) the relationships between the outcomes and explanatory variables are possibly nonlinear, (4) the signal to noise ratio in the real data may be low. To compare these methods ...


Manfaat Sunat Laser.Docx, Klinik Sentosa 2020 Bryant University

Manfaat Sunat Laser.Docx, Klinik Sentosa

Klinik Sentosa

Manfaat Sunat Laser? [Telp: 081366657878]. Manfaat sunat laser bertujuan mengangkat jaringan yang menutupi penis. Penutup ini biasanya dikenal dengan sebutan kulup. Sunat bisa dilakukan pada bayi laki-laki yang baru lahir, umumnya dilakukan pada anak dan dewasa.


Type One Diabetes Mellitus In Immigrant And Minority Pediatric Populations, Kristina Nielson 2020 Brigham Young University

Type One Diabetes Mellitus In Immigrant And Minority Pediatric Populations, Kristina Nielson

Student Publications

Type 1 diabetes mellitus (T1DM) is a prevalent chronic illness affecting children and adolescents. Globally, it is estimated that at least 1 million children under the age of 19 years are affected by T1DM. Immigrants and minorities have worse diabetic outcomes than the majority population. The purpose of this article is to identify common challenges in children with T1DM who are part of immigrant or minority populations. Major health challenges for children with T1DM who are immigrants or minorities include issues regarding access to healthcare, communication, and cultural adaptation. Access of children with T1DM to high-quality healthcare and new diabetes ...


Social-Ecological And Protective Factor Approach To Managing Parental Incarceration, Jacquelyn Harris 2020 National Louis University

Social-Ecological And Protective Factor Approach To Managing Parental Incarceration, Jacquelyn Harris

Dissertations

Mass imprisonment does not only impact the incarcerated individual; it also affects approximately five million children in the United States. Researchers identified and compare the impact of parental incarceration on child development. They acknowledged the protective factors across the lifecycle from a social-ecological perspective and specifically related to parental incarceration. The comprehensive literature review inspired an innovative model, the social-ecological and protective factor approach to managing parental incarceration. The primary goal of this model is to combat the detrimental effects of parental incarceration by identifying protective factors across the lifecycle and throughout the microsystem, mesosystem, and exosystem. This model is ...


Peer-Led Education Expedites De-Prescribing Proton Pump Inhibitors For Appropriate Veterans, Mary H. Bowman 2020 University of San Diego

Peer-Led Education Expedites De-Prescribing Proton Pump Inhibitors For Appropriate Veterans, Mary H. Bowman

Doctor of Nursing Practice Final Manuscripts

Costly proton pump inhibitors (PPIs) have been widely prescribed since the 1990’s for prevention and treatment of ulcers and gastroesophageal reflux disease (GERD). Evidence published since 2012 demonstrates risks associated with taking PPIs longer than eight weeks. Primary care providers (PCPs) mostly de-prescribe PPIs for persons not meeting criteria for long term use. Many patients resist discontinuation.

A three-month evidenced based practice (EBP) education project was conducted by a nurse practitioner to improve PCP peer de-prescribing successes with appropriate patients in an outpatient California based veteran Primary Care Clinic. Fifteen PCPs were pretested about usual care practices between two ...


Plant-Powered: A Digital Plant-Based Nutrition Intervention For Low-Income Patients With Type Ii Diabetes, Ellen Pelos 2020 The University of San Francisco

Plant-Powered: A Digital Plant-Based Nutrition Intervention For Low-Income Patients With Type Ii Diabetes, Ellen Pelos

Master's Projects and Capstones

Purpose: This project aimed to measure the acceptability and feasibility of plant-based diets among low-income individuals with type II diabetes at the Samaritan House Food Pharmacy and to create a user-centered pilot program to encourage the adoption of a plant-based diet.

Background: Plant-based diets are effective for preventing, treating, and reversing type II diabetes, but there is not much evidence about the acceptability and feasibility of these diets.

Methods: Focus groups were used to gather qualitative data about the acceptability and feasibility of plant-based diets in the target population. The researcher conducted interviews with Food Pharmacy program leaders to learn ...


Recruiting And Retaining Np Preceptors, Angelica Renteria 2020 The University of San Francisco

Recruiting And Retaining Np Preceptors, Angelica Renteria

DNP Qualifying Manuscripts

It is estimated that by 2020, the shortage of primary care providers will reach over 20,000. This has led to a surge of nurse practitioner (NP) programs across the nation. Recruiting and retaining preceptors is of paramount importance. Barriers and incentives to precepting must be identified in order to maximize teaching capacity. More effective ways of training NP students (NPs) need to be explored to capitalize on the time preceptors invest with students. The adoption of the OMP teaching model may facilitate training for the preceptor and improve the learning of NPs due to its simplicity and efficiency.


A Multidisciplinary Chronic Lung Disease Team In A Neonatal Intensive Care Unit Is Associated With Increased Survival To Discharge Of Infants With Tracheostomy, Taylor Hansen 2020 Children's Mercy Kansas City

A Multidisciplinary Chronic Lung Disease Team In A Neonatal Intensive Care Unit Is Associated With Increased Survival To Discharge Of Infants With Tracheostomy, Taylor Hansen

Research Days

No abstract provided.


The Evolving Management Of Aortic Valve Disease: Trends In The Utilization And Cost Of Savr, Tavr, And Medical Therapy, Andrew Goldsweig 2020 University of Nebraska Medical Center

The Evolving Management Of Aortic Valve Disease: Trends In The Utilization And Cost Of Savr, Tavr, And Medical Therapy, Andrew Goldsweig

Theses & Dissertations

Aortic stenosis (AS) and regurgitation (AR) may be treated with surgical aortic valve replacement (SAVR), transcatheter AVR (TAVR), or medical therapy (MT). Data are lacking regarding usage and cost of SAVR, TAVR, and MT for patients hospitalized with aortic valve disease. From the Nationwide Readmissions Database, we determined utilization and cost trends for SAVR, TAVR, and MT in patients with aortic valve disease admitted 2012-2016 for valve replacement, heart failure, unstable angina, non-ST-elevation myocardial infarction, or syncope. From 2012 through 2016, there was a 48.1% increase in the number of patients hospitalized for aortic valve disease annually. Overall, 19 ...


The Effect Of The Timing Of A Hospice Referral And The Perceived Quality Of Care By The Family, Caitlin Tran 2020 Dominican University of California

The Effect Of The Timing Of A Hospice Referral And The Perceived Quality Of Care By The Family, Caitlin Tran

Nursing | Senior Theses

Hospice care is a specialized type of palliative care for patients with a time-limiting illness. Despite its benefits, hospice remains underutilized. A key reason behind the underutilization are untimely referrals, often made during the last weeks or days of the patient’s life. The purpose of this paper is to investigate the existing barriers towards hospice that play into late referrals and its effect on patient/family satisfaction. This information will be examined to propose a pilot research study for further exploration.


The Effect Of Dance Movement Therapy On The Mood Of Hospitalized Psychiatric Adolescents, Amy Chiu 2020 Dominican University of California

The Effect Of Dance Movement Therapy On The Mood Of Hospitalized Psychiatric Adolescents, Amy Chiu

Nursing | Senior Theses

Mental illness in children has increased over all aspects throughout the years to right now (CDC, 2019). Many of these children do get treatment for these disorders but there are still a percent that do not receive any treatment or find effective ways to maintain non-pharmaceutical alternatives for mood stabilization. The alternative therapies that are introduced in hospital settings plays a role in allowing for alternative therapies to be apart of the treatment plan for patients. Dance Movement therapy (DMT) is an alternative therapy that uses movement to conduct change in patient’s emotions based on their own choices of ...


Bilingual Practices In Speech-Language Pathology In Nebraska Schools, Kylee Beyea 2020 University of Nebraska at Omaha

Bilingual Practices In Speech-Language Pathology In Nebraska Schools, Kylee Beyea

Theses/Capstones/Creative Projects

The United States is home to a population that is nearly 20% bilingual. A statistic such as this almost guarantees that speech-language pathologists (SLPs) will work with someone from this bilingual population at some point during their career. Many factors contribute to how children learn language, and there are added complexities in the acquisition of multiple languages which can complicate the job of a clinician. Silent periods, codeswitching, transfer, and other bilingual language phenomena make diagnosing speech and language disorders difficult. The American Speech-Language-Hearing Association (ASHA) provides guidelines and a code of ethics to be followed to ensure best practice ...


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