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Mitochondrial Aspects Of Neuronal Pathology In Triple-Transgenic Alzheimer’S Disease Mice, John Zachary Cavendish 2021 West Virginia University

Mitochondrial Aspects Of Neuronal Pathology In Triple-Transgenic Alzheimer’S Disease Mice, John Zachary Cavendish

Graduate Theses, Dissertations, and Problem Reports

Alzheimer’s disease (AD) is a fatal, progressive neurodegenerative disease afflicting millions of people in the United States alone and is the only one of the top leading causes of morbidity and mortality with no effective disease-modifying therapies. It is the most common form of dementia, affecting one in three people over the age of 85. While the hallmarks of the disease include accumulation of beta-amyloid-based extracellular plaques and hyperphosphorylated tau-based intracellular neurofibrillary tangles, treatment strategies centered on removing or mitigating these components of AD have all failed in humans. Mitochondrial dysfunction has been increasingly recognized as an early and ...


Safety Of Vitamin D2 Mushroom Powder As A Novel Food Pursuant To Regulation (Eu) 2015/2283, John Kearney, Dominique Turck, Jacqueline Castenmiller, Stefaan de Henauw 2020 Technological University Dublin

Safety Of Vitamin D2 Mushroom Powder As A Novel Food Pursuant To Regulation (Eu) 2015/2283, John Kearney, Dominique Turck, Jacqueline Castenmiller, Stefaan De Henauw

Articles

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scienti?c opinion on vitamin D2 mushroom powder as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is an ingredient produced from Agaricus bisporus mushrooms that have been exposed to ultraviolet (UV) light to induce the conversion of provitamin D2 (ergosterol) to vitamin D2 (ergocalciferol). The NF contains concentrations of vitamin D provided by vitamin D2 in the ranges of 1,000–1,300 lg/g. The information provided on the manufacturing process, composition ...


Health Care Terminology, James Clover 2020 California State University, San Bernardino

Health Care Terminology, James Clover

Q2S Enhancing Pedagogy

Course outline for the study of basic medical terminology by learning root words, prefixes and suffixes. The course focuses on correct pronunciation, spelling and use of medical terms. Anatomy, physiology, and pathology of disease are discussed yet no previous knowledge of these topics is necessary.


The Effects Of Increasing Running Speed On Vgrf And Asymmetry, Kaela M. Hierholzer 2020 East Tennessee State University

The Effects Of Increasing Running Speed On Vgrf And Asymmetry, Kaela M. Hierholzer

Electronic Theses and Dissertations

Biomechanical and physiological parameters related to running performance are usually studied separately. However, evaluating both aspects together could be beneficial in improving athletic performance. The purpose of this study was to observe the change in peak vGRF and asymmetry as speed increases, while observing physiological responses during a O2maxtest. Data from athlete monitoring of 12 cross-country and triathlon athletes were analyzed. The athlete monitoring protocol included three unweighted countermovement jumps and a O2maxtest performed by the athletes. The athletes had an average O2maxof 53.4 ± 7.7 mL/kg/min, while their average vGRF ...


The Evolving Management Of Aortic Valve Disease: Trends In The Utilization And Cost Of Savr, Tavr, And Medical Therapy, Andrew Goldsweig 2020 University of Nebraska Medical Center

The Evolving Management Of Aortic Valve Disease: Trends In The Utilization And Cost Of Savr, Tavr, And Medical Therapy, Andrew Goldsweig

Theses & Dissertations

Aortic stenosis (AS) and regurgitation (AR) may be treated with surgical aortic valve replacement (SAVR), transcatheter AVR (TAVR), or medical therapy (MT). Data are lacking regarding usage and cost of SAVR, TAVR, and MT for patients hospitalized with aortic valve disease. From the Nationwide Readmissions Database, we determined utilization and cost trends for SAVR, TAVR, and MT in patients with aortic valve disease admitted 2012-2016 for valve replacement, heart failure, unstable angina, non-ST-elevation myocardial infarction, or syncope. From 2012 through 2016, there was a 48.1% increase in the number of patients hospitalized for aortic valve disease annually. Overall, 19 ...


Titus Thesis Figures.Docx, Titus Hou 2020 University of Iowa

Titus Thesis Figures.Docx, Titus Hou

Titus Hou

No abstract provided.


Titus Thesis.Docx, Titus Hou 2020 University of Iowa

Titus Thesis.Docx, Titus Hou

Titus Hou

No abstract provided.


The Efficacy Of Extended-Release Eprinomectin For The Reduction Of Horn Flies, Face Flies, And Fecal Egg Counts Of Parasitic Nematodes In Replacement Beef Heifers, Sophia F. Landers 2020 University of Arkansas, Fayetteville

The Efficacy Of Extended-Release Eprinomectin For The Reduction Of Horn Flies, Face Flies, And Fecal Egg Counts Of Parasitic Nematodes In Replacement Beef Heifers, Sophia F. Landers

Animal Science Undergraduate Honors Theses

The purpose of this study was to evaluate the efficacy of extended-release eprinomectin against horn flies, face flies, and fecal egg counts of parasitic nematodes in crossbreed replacement beef heifers. Fifty-four heifers were randomly placed into three treatment groups (N=18 heifers/treatment). Group 1 was administered the labeled dosage of extended-release eprinomectin on day 0. Group 2 acted as the negative control. Group 3 received the anthelmintic injection once a quarter of the heifers in the group reached the threshold treatment level for horn flies (N=200 flies/animal; day 41). Nematode infections were measured via fecal egg counts ...


Florpyrauxifen-Benzyl Use In Arkansas Rice (Oryza Sativa L.), Hannah Elizabeth Wright 2020 University of Arkansas, Fayetteville

Florpyrauxifen-Benzyl Use In Arkansas Rice (Oryza Sativa L.), Hannah Elizabeth Wright

Theses and Dissertations

Florpyrauxifen-benzyl is a synthetic auxin herbicide which was commercially released in 2018 to combat troublesome grass, broadleaf, and sedge weed species in rice. Many factors may influence cultivar response to a new herbicide; hence, it is important to understand factors contributing to crop sensitivity to an herbicide in order to make appropriate recommendations. Prior to the onset of this study, research had been conducted on florpyrauxifen-benzyl in a flooded environment; however, none had been executed in a non-flooded environment. Experiments were conducted to evaluate the response of a long-grain variety ‘CL111’, a medium-grain variety ‘CL272’, and a long-grain hybrid ‘CLXL745 ...


Food Safety Risk In An Indoor Microgreen Cultivation System, Gina Marie Misra 2020 University of Arkansas, Fayetteville

Food Safety Risk In An Indoor Microgreen Cultivation System, Gina Marie Misra

Theses and Dissertations

Microgreens are immature sprouts of edible plants, sharing some similarities with sprouted seeds and petite leafy greens. Since they are most often grown in containers in buildings or greenhouses, they present a new area for food safety research at the intersection of the built environment and produce farming. Contamination by human pathogens has been extensively studied in other types of produce typically eaten raw, including sprouted seeds, which have been implicated in numerous outbreaks of salmonellosis over the last several decades. There is a paucity of knowledge about the microgreen sector of the fresh-cut industry; thus, it was determined that ...


Disease Ecology And Adaptive Management Of Brucellosis In Greater Yellowstone Elk, Gavin G. Cotterill 2020 Utah State University

Disease Ecology And Adaptive Management Of Brucellosis In Greater Yellowstone Elk, Gavin G. Cotterill

All Graduate Theses and Dissertations

Brucellosis is a bacterial infection that primarily affects livestock and can also be transmitted to humans. In the Greater Yellowstone Ecosystem (GYE), elk (Cervus canadensis) and bison (Bison bison) are habitual carriers of Brucella abortus, which arrived to the region with cattle over a century ago. The disease was eliminated from cattle in the United States through widespread control efforts, but is now periodically transmitted back to cattle on open rangelands where they can come into contact with fetal tissues and fluids from disease-induced abortions that occur among elk during the late winter and spring. In Wyoming, south of Yellowstone ...


The Utility Of Environmental Dna And Species Distribution Models In Assessing The Habitat Requirements Of Twelve Fish Species In Alaskan North Slope Rivers, James B. Eddings 2020 Utah State University

The Utility Of Environmental Dna And Species Distribution Models In Assessing The Habitat Requirements Of Twelve Fish Species In Alaskan North Slope Rivers, James B. Eddings

All Graduate Theses and Dissertations

Subsistence fishing is a vital component of Alaska’s North Slope borough economy and culture that is being threatened by human disturbance. These threats mean the fish must be protected, but the size of the region makes conservation planning difficult. Fortunately, advances in species distribution models (SDMs), environmental DNA (eDNA), and remote sensing technologies provide potential to better understand species’ needs and guide management. The objectives of my study were to: (1) map the current habitat suitability for twelve fish species, occurring in Alaska’s North Slope,(2) determine if SDMs based on eDNA data performed similarly to, or improved ...


A Case Study Comparing The Life Skills Development And Knowledge In Youth Participants Of Horseless And Traditional Horse Programs In Utah, Haley M. Johnson 2020 Utah State University

A Case Study Comparing The Life Skills Development And Knowledge In Youth Participants Of Horseless And Traditional Horse Programs In Utah, Haley M. Johnson

All Graduate Theses and Dissertations

Traditional horse 4-H programs develop life skills and knowledge in youth. Horseless horse programs lack evaluation for the same benefits. This study evaluated and compared four horseless and seven traditional horse participants from Washington County 4-H in Utah for gains in horse knowledge and development of 10 life skills that are commonly found in 4-H curriculum today: leadership, teamwork, self-responsibility, personal safety, problem solving, decision making, critical thinking, goal setting, communication, and concern for others.

The researcher conducted interviews to learn about life skill experiences of the horse program participants and discover what barriers prevented horseless youth from participating in ...


Interspecific Differences In Stressor Tolerance Drive Community-Level Changes In A Small Aquatic Ecosystem, Jennifer M. Weathered 2020 Utah State University

Interspecific Differences In Stressor Tolerance Drive Community-Level Changes In A Small Aquatic Ecosystem, Jennifer M. Weathered

All Graduate Theses and Dissertations

The global human population is expected to reach 9.8 billion by 2050 and an increase in food yield will be needed to provide for the future generations. Insects are among the biggest threats to food production and are therefore the subject of intense chemical control through the application of pesticides. The ability of insects to evolve resistance to pesticides after repeated use has been documented. However, how evolved responses affect individuals’ behaviors, their interactions with others, and how these factors impact overall patterns in distribution remains relatively unexplored in the bromeliad.

The aquatic insect communities housed in water-holding tropical ...


An Evaluation Of Management Options For The Clover Root Curculio (Sitona Hispidulus), A Pest Of Alfalfa (Medicago Sativa) In The Intermountain West, Kaitlin A. Rim 2020 Utah State University

An Evaluation Of Management Options For The Clover Root Curculio (Sitona Hispidulus), A Pest Of Alfalfa (Medicago Sativa) In The Intermountain West, Kaitlin A. Rim

All Graduate Theses and Dissertations

The clover root curculio (CRC) is an important forage pest throughout North America. Extensive larval feeding on host roots has been associated with reduced stand establishment, disruption of nutrient and water uptake, increased secondary plant pathogen infection, decreased winter plant survival, and reductions in forage quality and yield. Due to the hidden nature of larvae in the soil, CRC is often overlooked and integrated pest management programs are limited as there is a lack of management options. First, I surveyed northern Utah alfalfa for CRC natural enemies, particularly insect-attacking nematodes and fungi (entomopathogens) that could be used in biological control ...


Crispr/Cas9-Mediated Gene Editing In Herda Equine, Joseph R. Hawkes 2020 Utah State University

Crispr/Cas9-Mediated Gene Editing In Herda Equine, Joseph R. Hawkes

All Graduate Theses and Dissertations

HERDA (Heritable Equine Regional Dermal Asthenia) is a genetic skin disease mainly found in Quarter Horses, but also in Appaloosa and American Paint breeds. HERDA is similar to Ehlers-Danlos syndrome in humans, with symptoms including stretchy skin, hyperflexible joints, and, unique to HERDA equine, spontaneous skin sloughing. Horses affected by HERDA are not suitable for performing and are oftentimes euthanized. Some carriers for the HERDA-mutation are very competitive in the American Quarter Horse industry, especially in cutting events where it is believed, yet unproven, to give them an advantage with increased flexibility. It is also possible that the genomic locus ...


The Influence Of Protein Concentration And Homogenization On Moisture Content, Curd Yield, And Fat Retention Of Model Cheese Made From Microfiltered Skim Milk Recombined With Cream, Richard Byron Geslison 2020 Utah State University

The Influence Of Protein Concentration And Homogenization On Moisture Content, Curd Yield, And Fat Retention Of Model Cheese Made From Microfiltered Skim Milk Recombined With Cream, Richard Byron Geslison

All Graduate Theses and Dissertations

This project was funded by the Western Dairy Center at Utah State University as part of a multi-pronged approach to improve the current understanding of using concentrated milks in cheese making. Concentrated milk for this study was provided by South Dakota State University.

This study compared the effect of different concentration factors of milk on curd moisture levels, fat content, and cheese curd yields. To see if these results could be improved (i.e. remove more moisture and retain more fat) milk samples were also subjected to limited pressure homogenization (microfluidization) treatments.

It was found in the course of this ...


Patterns Of Microbial Diversity And Community Composition In Slot Canyons, Rock Pools, And Other Ephemeral And Perennial Aquatic Habitats, Marley Madsen 2020 Utah State University

Patterns Of Microbial Diversity And Community Composition In Slot Canyons, Rock Pools, And Other Ephemeral And Perennial Aquatic Habitats, Marley Madsen

All Graduate Theses and Dissertations

Microbes are the most diverse life forms on the planet and perform many important ecological functions. However, despite the abundance, diversity, and ecological importance of microbes they are often overlooked and understudied in many natural systems, including freshwater habitats. This thesis details the first ever investigation of the microbial diversity and community composition within fresh water rock pools and slot canyons of the Colorado Plateau, Utah. The purpose of the study was to determine the relative importance of various microbial community assembly processes. This thesis also includes a meta-analysis of the microbial alpha diversity in other perennial and ephemeral aquatic ...


Do Didymosphenia Geminata Blooms Affect Fishes In The Kootenai River Basin?, Niall G. Clancy 2020 Utah State University

Do Didymosphenia Geminata Blooms Affect Fishes In The Kootenai River Basin?, Niall G. Clancy

All Graduate Theses and Dissertations

Didymosphenia geminata (Didymo) is a nuisance algae that can cover entire streambeds under certain environmental conditions. Numerous studies have shown that it changes the composition of stream invertebrates. Fishes in many headwaters are known to feed almost exclusively on invertebrates. Thus, there is concern changes to the amount or type of invertebrates caused by Didymo blooms will impact fishes such as trout, charr, and sculpin. In the Kootenai River basin of Montana and British Columbia, we examined stream invertebrates and fish diets, condition, and growth across 25 streams during the summers of 2018 and 2019. The severity of Didymo blooms ...


Salinity Tolerance In Kentucky Bluegrass Hybrids, Paul G. Harris 2020 Utah State University

Salinity Tolerance In Kentucky Bluegrass Hybrids, Paul G. Harris

All Graduate Theses and Dissertations

Diminishing water sources in the Intermountain West have led to increased use of alternative sources of water. These sources, such as reclaimed water, generally have elevated salinity levels that may slow growth, and cause a decline in turfgrass quality. Kentucky bluegrass (Poa pratensis L.) is sensitive to salt stress, but is otherwise very well adapted to many turfgrass areas because of its dark color, durability, ability to recover from wear, and soft texture. Because of these positive traits, it has been the subject of selection for salt tolerance. This study was designed to evaluate the salt tolerance of hybrids from ...


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